Forum Post: Autism Nation: America's Chemical Brain Drain

Autism Nation: America's Chemical Brain Drain

Thursday, 24 April 2014 09:04
By Dr Brian Moench, Truthout | News Analysis

http://www.truth-out.org/news/item/23267-autism-nation-americas-chemical-brain-drain

While autism rates in Europe have remained virtually flat for the last decade, in the US, they have risen from 1:10,000 in 1981 to 1:68 in 2014. Many studies point to the prevalence of toxins in our environment as the culprit.

As flowers burst on the scene, blossoms unfold, and lawns awaken from winter's sleep, nature's spring rituals are joyful to watch.

Unfortunately, many home owners, gardeners, landscapers, farmers and state agencies launch an anti-nature spring ritual - mounting an arsenal of poisons to kill insects and weeds. This ritual comes at a tremendous cost.

"It's time to start looking for the environmental culprits responsible for the remarkable increase in the rate of autism in California." - Irva Hertz-Picciotto, epidemiology professor at University of California, Davis.

Last month, leading scientists warned of a "silent pandemic," citing strong evidence that "children worldwide are being exposed to unrecognized toxic chemicals that are silently eroding intelligence, disrupting behaviors, truncating future achievements and damaging societies." These "brain" toxins - heavy metals, fluoride, chemicals like PCBs, toluene, solvents, flame retardants, BPA, phalates and pesticides - are found in the furniture you sit on, the clothing you wear, the air you breathe, the food you eat and soil your kids play in.

And this short list of chemicals and compounds is just the tip of a very large toxic iceberg.

"It's time to start looking for the environmental culprits responsible for the remarkable increase in the rate of autism in California," said Irva Hertz-Picciotto, an epidemiology professor at University of California, Davis.

In 1981, the autism (ASD) rate in the United States was 1:10,000. In 2007, it was 1:150. In 2009, it was 1:100. In 2012, it was 1:88. In 2014, it is 1:68. At this rate of increase, by 2025 it will be 1:2, or 50 percent. For those of you tempted to think this is just greater awareness and expansion of the criteria for diagnosis, the CDC says that since the 2012 estimate of 1 in 88 children identified with ASD, the criteria used to diagnose, treat, and provide services have not changed, but the rate has increased another 30 percent.

Meanwhile, autism rates in Europe have remained virtually flat for the last decade. Recent estimates in European countries range from 1 in 5,000 in Germany to 1 in 700 in Portugal. So what are Americans doing to harm themselves and their children's brains that Europeans aren't, besides watching Fox News?

No one knows for sure, but one thing to consider is the massive increase in Genetically Modified Organisms (GMOs) and the concomitant upsurge in pesticide and herbicide use.

David Vogel, professor at the Haas School of Business and in the Department of Political Science at the University of California, Berkeley, points out that between 1960 and 1990, American health, safety, and environmental regulations were more stringent, risk averse, comprehensive, and innovative than those adopted in Europe. Vogel's book, The Politics of Precaution, explains that since around 1990, global regulatory leadership has shifted to Europe.

With many types of environmental risks, extreme conservative ideologues in the US have brought regulatory protection of public health to a screeching halt. America's failure to deal with the climate crisis is probably the most conspicuous casualty. But what is happening to the brains of our children may be just as important.

In more than 60 countries around the world, including Australia, Japan, and all of the countries in the European Union, there are significant restrictions or outright bans on the production and sale of GMOs. In the US, federal agencies have approved the GMO/pesticide industrial agriculture system based on studies conducted by the same corporations that created them and profit from their sale.

In more than 60 countries around the world, including Australia, Japan, and all of the countries in the European Union, there are significant restrictions or outright bans on the production and sale of GMOs.

The best-selling herbicide in the world is glyphosate, originally patented and sold by Monsanto as Roundup. Glyphosate is a potent endocrine disruptor, meaning it can interfere with the production, release, transport, metabolism, or elimination of the body's natural hormones, which are the most potent biologic substances known to science. Fetuses and infants are particularly at risk, as any disruption of endocrine systems can affect brain development. Last week a study was done that proved yet again Monsanto has been lying to the public. Monsanto has defiantly proclaimed all along that Roundup breaks down quickly and doesn't accumulate in the human body. Not so. Moms Across Americas examined the breast milk of ten American women and found alarmingly high levels of the primary active ingredient in Roundup, glyphosate, in three of the ten women. The study also examined urine from 35 people across the country and found glyphosate at levels ten times higher than a similar survey done in a European population. Monsanto and regulatory bodies worldwide have based all of their regulations on the assumption that glyphosate is not bio-accumulative. Senior Monsanto scientist Dan Goldstein even recently stated, "If ingested, glyphosate is excreted rapidly, does not accumulate in body fat or tissues, and does not undergo metabolism in humans. Rather, it is excreted unchanged in the urine."

Other research suggests an even longer list of toxic substances can irreversibly interfere with the delicate process of organizing fetal brain architecture.

Recent research published in the New England Journal of Medicine compared brain autopsies of autistic children, who had died from unrelated causes, to those of normal children. Autistic brains demonstrated abnormal patches of disorganized neurons disrupting the usual distinct layers in the brain's cortex. The primary implication of the research is the abnormalities almost certainly had to have occurred in utero during key developmental windows between 19 to 30 weeks gestation. Perhaps even more important than the dose of a toxin is the timing of the exposure, and presence or absence of other facilitators or synergistic toxins. Other research suggests an even longer list of toxic substances can irreversibly interfere with the delicate process of organizing fetal brain architecture. It is a popular misconception, fed in part by weak government regulations, that toxins produce an all or nothing effect. Levels above "safe" doses are acknowledged to be harmful, but below "safe" levels are misinterpreted as harmless. But that's not how the body works, especially the developing brain.

Brain-damaging chemicals can provoke the entire spectrum of outcomes, from imperceptible changes to severe neurologic handicaps. Furthermore, the absence of cognitive or behavioral problems in childhood is not necessarily evidence that an early exposure to a neurotoxin had no adverse effect on brain development. In fact, studies in both animals and humans have demonstrated that some substances cause damage to the brain that is manifested only in the delayed onset of learning problems, attention deficits, and changes in emotional regulation, which can have long-term consequences in teenage and adult years.

The immature brain of an embryo, fetus, or infant is at risk for significant and permanent damage from exposure to chemicals, like pesticides, at levels that may have no detectable impact on adults. Consequently public policies that too often focus on adults fail to protect developing brains during pregnancy and early infancy.

Many pesticides are merely derivations of chemical warfare agents of the World War I and World War II era, i.e. nerve gases.

Most pesticides work by causing chemical disruption of the brain and nervous system of insects. In fact, many pesticides are merely derivations of chemical warfare agents of the World War I and World War II era, i.e. nerve gases. It should be no surprise, then, that human nerve cells could also be affected, especially when considering that at the critical embryonic stage, the human fetal brain is no larger than that of many insects. Research confirms that mothers more exposed to commonly used, "safe" pesticides bear children with lower intelligence (1,2,3,4,5), structural brain abnormalities (6), behavioral disorders, compromised motor skills (7,8), higher rates of brain cancer (9), and smaller head size (10).